BiG-SCAPE classes

By default, BiG-SCAPE will try to separate clusters into eight classes. This is done based on the product annotation from antiSMASH (see here). New labels introduced in antiSMASH 5 and 6 are annotated with a superscript.

The rules followed are currently:

antiSMASH annotation	BiG-SCAPE class
t1pks, T1PKS^5	PKS I
transatpks, t2pks, t3pks, otherks, hglks, transAT-PKS^5, transAT-PKS-like^5, T2PKS^5, T3PKS^5, PKS-like^5, hglE-KS^5 and combinations of these with {t1pks, T1PKS^5} or themselves	PKS other
nrps, NRPS^5, NRPS-like^5, thioamide-NRP^5, NAPAA^6	NRPS
lantipeptide, thiopeptide, bacteriocin, linaridin, cyanobactin, glycocin, LAP, lassopeptide, sactipeptide, bottromycin, head_to_tail, microcin, microviridin, proteusin, guanidinotides, RiPP-like, lanthipeptide^5, lipolanthine^5, RaS-RiPP^5, fungal-RiPP^5, thioamitides^5.1, lanthipeptide-class-i^6, lanthipeptide-class-ii^6, lanthipeptide-class-iii^6, lanthipeptide-class-iv^6, lanthipeptide-class-v^6, ranthipeptide^6, redox-cofactor^6, RRE-containing^6, epipeptide^6, cyclic-lactone-autoinducer^6, spliceotide^6 and combinations of these	RiPPs
amglyccycl, oligosaccharide, cf_saccharide, saccharide^5 and combinations of these	Saccharides
terpene	Terpene
any of {PKS I} + any of {NRPS}	PKS/NRPS Hybrids
acyl_amino_acids, arylpolyene, aminocoumarin, ectoine, butyrolactone, nucleoside, melanin, phosphoglycolipid, phenazine, phosphonate, other, cf_putative, resorcinol, indole, ladderane, PUFA, furan, hserlactone, fused, cf_fatty_acid, siderophore, blactam, fatty_acid^5, PpyS-KS^5, CDPS^5, betalactone^5, PBDE^5, tropodithietic-acid^5, NAGGN^5, halogenated^5, pyrrolidine^6 and any combined annotation	Others
*	< mix >

Hybrids

If the hybrids mode is enabled, some clusters could be analyzed in different classes (if those are valid classes):

If cluster is the PKS-NRP_Hybrids BiG-SCAPE class: the cluster will also be put in the NRPS class and one of the PKS classes (PKS I or PKS other). If the cluster contains the t1pks annotation, it will always be put on the PKS I class.

If the cluster is classified as Others and BiG-SCAPE detects that it's because of a multiple annotation (e.g. terpene-t1pks), BiG-SCAPE will also put the cluster in every different individual class.